B. melitensis is usually transferred onto healthy animals by infected animal from the herd. This is why any new additions to the herd should be test. Control of brucellosis can be carried out by running tests on animas and removal of positive reactors from the herd. Interestingly enough, infected goats, following miscarriage or a normal birth, continue to secrete the infectious agent via vaginal secretion, whereas in sheep this period is shorter and is typically 2 to 3 weeks in duration. This is why it is necessary to remove any positive reactors from the herd as soon as possible, aborted material should be disposed off and burned and each site exposed to infected animals or contaminated aborted material should be meticulously cleaned and disinfected (most commercially available disinfectants such as solutions of hypochlorite, 70% ethanol, isopropanol, iodoforms, 2% to 3% caustic soda and other similar disinfectants are all efficient against Brucella).
Sterilization of kits and equipment (used by veterinaries, physicians) are preformed in dry-heat environment [160-170°C for at least 1 hour]. Solutions can be decontaminated by boiling for 10 minutes. Inactivation of infectious agents in liquid stable dung can be successfully preformed in 2 to 4 weeks using xilen (1ml/liter) and calcium cyanamide (20 kg/m3). In many countries, live attenuated Rev 1 vaccines are used to exercise control of infections caused by B. melitensis.